2024 Sperm associated antigen 6

Sperm associated antigen 6

Author: yxft

August undefined, 2024

WebAug 1, 2024 · Sperm-associated antigen 6 (SPAG6) is the mammalian orthologue of Chlamydomonas PF16, an axonemal central pair protein involved in flagellar motility. In mice, two Spag6 genes have been identified. WebSperm-associated antigen 6 (SPAG6) is the mammalian orthologue of Chlamydomonas PF16, an axonemal central pair protein involved in ﬂagellar motility. In mice, two Spag6 …

SPAG6 Gene - GeneCards SPAG6 Protein SPAG6 Antibody

WebSep 22, 2024 · Sperm-associated antigen 6 (SPAG6) is an ortholog of chlamydia PF16, located at the chromosomal region 10p12.2 . SPAG6 was originally identified in human testicular tissues and plays a role in regulating germ cell … WebOct 21, 2014 · SPAG6, an axoneme central apparatus protein, is essential for function of ependymal cell cilia and sperm flagella. A significant number of Spag6 -deficient mice die … thalassemia marriage test

Planar cell polarity defects and hearing loss in sperm-associated ...

WebApr 7, 2006 · Southern blot analysis determined that SPAG6 is highly conserved in primates and that a homolog is present in rodents. Western blot analysis showed that SPAG6 is … WebApr 12, 2024 · The claudin 18.2 (CLDN18.2) antigen is frequently expressed in malignant tumors, including pancreatic ductal adenocarcinoma (PDAC). Although CLDN18.2-targeted CAR-T cells demonstrated some therapeutic efficacy in PDAC patients, further improvement is needed. One of the major obstacles might be the abundant cancer-associated … thalassemia major treatment in india

SPAG6 Antibody (3E3) (H00009576-M01): Novus Biologicals

Sperm Associated Antigen 6 (SPAG6) Regulates …

WebJul 1, 2015 · Sperm-associated antigen 6 (Spag6) is a Chlamydomonas reinhardtii PF16 homologous gene detected in the human testis and is crucial for sperm motility. Neuronal migration is a dynamic process requiring coordinated cytoskeletal remodeling, and Spag6 is co-localized with microtubules in Chinese hamster ovary cells and COS-1 cells. However, … WebMay 12, 2016 · Sperm associated antigen 6 (SPAG6), a component of the central apparatus of the “9 + 2” axoneme, plays a central role in ciliary and flagellar motility; but, its contribution to adaptive immunity... synonyms of reach outWebMay 12, 2016 · Sperm associated antigen 6 (SPAG6), a component of the central apparatus of the “9 + 2” axoneme, plays a central role in ciliary and flagellar motility; but, its … thalassemia major is also known as

"WebOct 30, 2024 · Sperm-associated antigen 5 (SPAG5) is a mitotic spindle-associated protein that is involved in various biological processes in cervical cancer and bladder urothelial … " - Sperm associated antigen 6

Sperm associated antigen 6

WebIn addition, extracellular sperm- ine and spermidine exhibit anti-inflammatory properties (Soda et al., 2005; Zhang et al., 1997). Inflammation is considered to be a factor accelerating the progression of age-associated pathologies (Franceschi et al., 2000). ... the expression of lymphocyte function-associated antigen-1 (LFA-1) on the surface ... WebMammalian SPAG6, the orthologue of Chlamydomonas reinhardtii PF16, is a component of the central apparatus of the '9 + 2' axoneme that controls ciliary/flagellar motility, …

Did you know?

WebApr 7, 2006 · 605730 - SPERM-ASSOCIATED ANTIGEN 6; SPAG6 - SPAG6 Sperm plasma membrane antigens are attractive antifertility vaccine targets because antibodies to them impair sperm function and have been found in a subset of infertile couples as well as in many vasectomized men in whom infertility has persisted after vasectomy reversal. WebSep 10, 2024 · Accumulated evidence shows that sperm-associated antigen 6 (SPAG6) gene has multiple biological functions. It maintains the normal function of a variety of cells …

WebDec 8, 2024 · SPAG6 sperm associated antigen 6 Gene ID: 9576, updated on 8-Dec-2024 Gene type: protein coding Also known as: pf16; CT141; FAP194; CFAP194; Repro-SA-1 See all available tests in GTR for this gene Go to complete Gene record for SPAG6 Go to Variation Viewer for SPAG6 variants Summary WebSperm-associated antigen 6 is a protein that in humans is encoded by the SPAG6 gene.[4][5] For faster navigation, this Iframe is preloading the Wikiwand page for Sperm-associated …

WebMar 1, 2024 · The sperm-associated antigen 6 (SPAG6; MIM: 605,730) gene encodes an axonemal protein that plays a critical role in axonemal structural integrity and function . SPAG6 is primarily expressed in the lung and testis, and its variants are associated with multi-system dysfunctions involving cilia and flagella [ 14 , 15 ], including primary ciliary ... WebNov 20, 2015 · Sperm Associated Antigen 6 (SPAG6) Regulates Fibroblast Cell Growth, Morphology, Migration and Ciliogenesis Scientific Reports Open Access Published: 20 …

WebOct 21, 2014 · SPAG6, an axoneme central apparatus protein, is essential for function of ependymal cell cilia and sperm flagella. A significant number of Spag6-deficient mice die with hydrocephalus, and surviving males are sterile because of sperm motility defects. In further exploring the ciliary dysfunction in Spag6-null mice, we discovered that cilia beat …

WebImproved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm agglutinating antibodies from an infertile woman. thalassemia major cureWebJul 1, 2009 · Sperm associated antigen 6 (SPAG6), a sperm protein, has been linked with sperm flagellar motility and structural integrity of the axoneme central apparatus of mature sperm in mice and humans. Sperm proteins especially those associated with sperm motility are potential biochemical targets for therapeutic or contraceptive management. Detection ... synonyms of ravishedWebInfertility is a major health issue, estimated to affect ~15% of the global population ( 1 ). Human reproduction requires normal developmental processes consisting of the production of competent gametes, fertilization, preimplantation embryonic development, implantation, pregnancy, and birth. Several biological processes, including organ ... thalassemia mayor pdfWebJan 20, 2024 · Sperm-associated antigen 6 (SPAG6) is the mammalian orthologue of Chlamydomonas PF16, an axonemal central pair protein involved in flagellar motility. In … thalassemia mayo clinicWebNov 13, 2014 · Sperm associated antigen 6 (SPAG6) is the orthologue of Chlamydomonas PF16. Dysfunction of PF16 gives rise to paralyzed flagella in Chlamydomonas [12] It has been reported that Spag6- deficient mice develop hydrocephalus, and the males are sterile due to sperm motility defects [13] , [14] . thalassemia mcv indexWebDec 8, 2024 · SPAG6 sperm associated antigen 6 [Homo sapiens (human)] - Gene - NCBI NCBI Skip to main content Skip to navigation Resources All Resources Chemicals & Bioassays BioSystems PubChem BioAssay PubChem Compound PubChem Structure Search PubChem Substance All Chemicals & Bioassays Resources... DNA & RNA thalassemia minor and diabetesWebDec 1, 2024 · The mouse sperm-associated antigen 6 ( Spag6) gene, the orthologue of Chlamydomonas PF16, encodes a 55.3-kDa polypeptide that is a component of the axoneme central apparatus of flagella and motile cilia.1 SPAG6 is ubiquitously expressed in tissue and organs containing ciliated cells, such as in the central nervous system, respiratory … synonyms of recklessness