Solubility of theophylline in water
WebJun 24, 2024 · This study aimed to assess the use of semi-solid extrusion-based 3D printing for the preparation of tailored doses of theophylline in the form of a chewable dosage form ... respectively. However, more importantly, GBP is freely soluble in water, whereas TPH is only slightly soluble in water [43,44], giving rise to a higher ... WebThe solubility of theophylline – oxalic acid co-crystal and theophylline – glutaric acid co-crystal was determined in 4:1 chlroform – methanol and in pure chloroform respectively. At equilibrium with the solid theophylline – oxalic acid co-crystal, the theophylline concentration is only 60 % of the corresponding value for the
Solubility of theophylline in water
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WebOct 9, 2013 · In this paper, the influence of polymorphs on the transformation water activity that corresponds to the transformation between hydrate and anhydrate of theophylline was investigated. Theophylline is known to exist either as anhydrates or a monohydrate. The transformation water activities of theophylline form II and IV were determined …
WebAug 1, 2024 · The equilibrium solubility of caffeine and theophylline were determined in {methanol + water} binary mixtures at 298.15 K by means of the shaken flask method and … WebJan 2, 2024 · Chemsrc provides Theophylline(CAS#:58-55-9) MSDS, density, melting point, boiling point, structure, formula, ... Solubility in water: slightly soluble Specific Gravity/Density: Molecular Formula: C7H8N4O2 Molecular Weight: 180.17 Section 10 - STABILITY AND REACTIVITY
WebTheophylline is a dimethylxanthine having the two methyl groups located at positions 1 and 3. It is structurally similar to caffeine and is found in green and black tea. It has a role as a vasodilator agent, a bronchodilator agent, a muscle relaxant, an EC 3.1.4.* (phosphoric … WebJun 23, 2009 · The enthalpies of solution $$ \\Updelta_{sol}^{{}} H_{m}^{{}} $$ of polymorphic forms I and II of theophylline in water at 298.15 K using the isoperibol solution calorimeter have been determined in the range of concentration (0.311–1.547) · 10−3 /mol · kg−1. The enthalpies of hydration $$ \\Updelta_{hyd}^{{}} H_{m}^{o} $$ were determined …
WebHowever, theophylline is only sparingly soluble in water and alcohol. The solubility of theophylline in water is 5.5 mg/mL, whereas in methanol and ethanol is 0.699 mg/mL and …
Web[Water soluble theophylline] [Water soluble theophylline] G Med Mil. Jul-Aug 1955;105(4):369-73. [Article in Italian] Author R RUGGIERI. PMID: 13277851 No abstract … freeman\u0027s journal irelandWebIncreasing the oral bioavailability of poorly water-soluble carbamazepine using immediate-release pellets supported on SBA-15 mesoporous silica Zhouhua Wang,1,2 Bao Chen,1 Guilan Quan,1 Feng Li,1 Qiaoli Wu,1 Linghui Dian,1 Yixuan Dong,1 Ge Li,2 Chuanbin Wu1,21School of Pharmaceutical Sciences, 2Research and Development Center of … freeman\u0027s houseWebDimensional changes, gel layer evolution and drug release studies in hydrophilic matrices loaded with drugs of different solubility K Avgoustakis 2007, International Journal of Pharmaceutics freeman\u0027s hospital phone numberWebJan 1, 1975 · Melting Range The original synthetic literature27 reported a melting point 0 ; 264O for theophylline subsequently the melting range has been reported to be between 271° and 274O C.28 c Solubility The reported solubility of theophylline is 8.3 mg/ml in water; 12.5 mg/ml in ethanol; 11.f,Tg/ml in , Several chloroform; and sparingly soluble in ... freeman\u0027s halifax nsWebTheophylline is a cyclic phosphodiesterase inhibitor. It antagonizes Adenosine A Receptors and weakly inhibits alkaline phosphodiesterases and 5′-nucleotidase. ... Soluble in water (8.3 g/l) at 20° C, 0.1 M NaOH, 0.1 M HCl, ethanol (moderately), DMSO, alkali hydroxides, ammonia, dilute hyrochloric acid, nitric acid, ... freeman\u0027s little new york halifaxWebAminophylline is soluble in water and insoluble in alcohol. Theophylline occurs as bitter-tasting, odorless, white, crystalline powder with a melting point between 270-274°C. It is sparingly soluble in alcohol and only slightly soluble in water at a pH of 7, but solubility increases with increasing pH. freeman\u0027s lumber mill greenfieldWebCommon-Ion Effect. The common-ion effect is a term that describes the decrease in solubility of an ionic compound when a salt that contains an ion that already exists in the chemical equilibrium is added to the mixture. This effect best be explained by Le Chatelier's principle.Imagine if the slightly soluble ionic compound calcium sulfate, CaSO 4, is added … freeman\u0027s little new york lower sackville