Peroxisome proliferator-activated receptor 伪
WebJul 1, 2007 · To explore the effects of the simultaneous activation of liver X receptor (LXR) and peroxisome proliferator-activated receptor alpha (PPARalpha) on bile acid biosynthesis in rats. WebApr 12, 2024 · To investigate the molecular mechanisms underlying autophagy inducing pulmonary vascular remodeling and rosiglitazone inhibiting pulmonary arterial …
Peroxisome proliferator-activated receptor 伪
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In the field of molecular biology, the peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor proteins that function as transcription factors regulating the expression of genes. PPARs play essential roles in the regulation of cellular differentiation, development, and … See more Three types of PPARs have been identified: alpha, gamma, and delta (beta): • α (alpha) - expressed in liver, kidney, heart, muscle, adipose tissue, and others • β/δ (beta/delta) - expressed in many tissues, especially in See more All PPARs heterodimerize with the retinoid X receptor (RXR) and bind to specific regions on the DNA of target genes. These DNA sequences are … See more Like other nuclear receptors, PPARs are modular in structure and contain the following functional domains: • (A/B) - N-terminal region • (C) DBD - DNA-binding domain • (D) - flexible hinge region See more • Metabolic syndrome • Endocannabinoid system See more The three main forms of PPAR are transcribed from different genes: • PPARα - chromosome 22q12-13.1 (OMIM 170998 See more PPARα and PPARγ are the molecular targets of a number of marketed drugs. For instance the hypolipidemic fibrates activate PPARα. The anti diabetic thiazolidinediones activate PPARγ. The synthetic … See more • [1] (PPAR Resource Page, Penn State University). • [2] (Nuclear Receptor Resource). • PPAR reference outline Archived 2024-02-14 at the Wayback Machine (Rutgers University). See more WebMar 21, 2024 · Peroxisome proliferator-activated receptors (PPARs) are essential nuclear hormone receptors regulating metabolic processes, and they participate in the initiation and progression processes of tumors. Gastrointestinal (GI) cancer is a prevalent malignancy worldwide that originates from the tissues of the gastrointestinal tract and is ...
WebJul 21, 2003 · Peroxisome proliferator-activated receptors (PPAR) are nuclear receptors acting as transcription factors on numerous target genes after heterodimerization with the retinoid X receptor. PPAR-α and PPAR-γ may be activated by different agonists, although the endogenous ligands are unknown. WebMar 9, 2024 · Peroxisome proliferator-activated receptor-γ coactivator (PGC)-1α is a transcriptional coactivator described as a master regulator of mitochondrial biogenesis …
Web上海极威生物科技有限公司成立于上海，经过多年的努力发展已成为专业供应各类生物科研用品的公司，长期专注于生物领域，旗下产品种类众多， 特别是 elisa试剂盒这一产品已使极威生物成为业内知名公司。 上海极威 秉承 以产品质量为根本，以市场需求为导向，以为客户创造价值为己任的精神 ... WebApr 23, 2024 · Peroxisome proliferator-activated receptor α (PPARα) is a nuclear receptor that modulates hepatic lipid homeostasis and affects NASH progression. [ 6] PPARα agonists such as fibrates are widely prescribed for the treatment of dyslipidemias as lipid-lowering drugs in the clinic. [ 7]
WebFeb 20, 2024 · Peroxisome proliferator activated receptor α (PPARα), a drug target for dyslipidemia, is known to be downregulated in cardiomyocytes in response to hypertrophic stimuli. The current study was undertaken to investigate the role of PPARα signaling in mitochondrial remodeling and thereby dysregulation of cardiomyocytes due to …
WebPeroxisome-proliferator activator receptors (PPARs) form a family of nuclear hormone-activated receptors and transcription factors that regulates the function and expression … rubble chasehttp://www.yi7.com/sell/show-5512699.html rubble chute screwfixWebPeroxisome proliferator-activated receptor γ (PPARγ) is a ligand-activated nuclear receptor that regulates cellular lipid and glucose metabolism and also plays an inhibitory role in … rubble chute bracketWebMar 25, 2024 · Growing evidence suggests a role for peroxisome proliferator-activated receptor β/δ (PPAR β/δ) in the angiogenesis, growth, and metastasis of solid tumors, but little is known about its role in multiple myeloma (MM). Angiogenesis in the bone marrow (BM) is characteristic of disease transition from m … rubble collection norfolkrubble collection kirkleesWebAug 3, 2024 · Sterol regulatory element binding protein (SREBP)-1c is a transcription factor that regulates lipid synthesis from glucose in the liver. It is activated by sucrose, which activates the fatty acid synthesis pathway. On the other hand, peroxisome proliferator-activated receptor (PPAR) α regulates the transcription of several genes encoding … rubble chase marshallWebDec 23, 2016 · The first peroxisome proliferator-activated receptor or PPAR was discovered as hormone receptor that was activated by rodent hepatocarcinogens that induced … rubble chutes for sale