Guanylation翻译
WebFormation of protein Cys-cGMP adducts by 8-nitro-cGMP was identified as a new post-translational modification, which we call protein S-guanylation. 8-Nitro-cGMP seems to regulate the redox-sensor signaling protein Keap1, via S-guanylation of the highly nucleophilic cysteine sulfhydryls of Keap1. http://www.ichacha.net/granulation.html
Guanylation翻译
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WebJul 19, 2024 · Notably, we discovered guanylation at the 3′ termini of mRNAs in HeLa cells, expanding the complexity of mRNA tails ().Unlike U tails, guanylated tails were found mainly among long A tails [≥~25 nucleotides (nt)] and were detected in a form of single-nucleotide addition ().Guanosine residues were located mainly at the 3′ terminal or penultimate … WebDec 5, 2024 · Although endogenous cGMP modification (S-guanylation) of bacteria was demonstrated to accelerate ubiquitin-mediated selective autophagic clearance, questions such as whether S-guanylation alone is sufficient to induce selective autophagy and whether S-guanylation could serve as a tag only in antibacterial autophagy (xenophagy) …
WebApr 3, 2014 · 蛋白翻译后修饰是细胞生命活动的基本形式之一，也是细胞精细调控其诸多生理过程关键生物学通路之一，并与很多疾病的发生发展休戚相关。 因此，负责蛋白翻译 … WebGuanylation proceeded efficiently upon treatment of the various amines with cyanamide in the presence of catalytic amounts of scandium(III) triflate under mild conditions. The method did not require the guanylation reagents to be preactivated, and the reaction proceeded efficiently in water. The method, therefore, has practical utility for ...
WebSep 30, 2007 · Formation of protein Cys-cGMP adducts by 8-nitro-cGMP was identified as a new post-translational modification, which we call protein S-guanylation. 8-Nitro-cGMP seems to regulate the redox-sensor ... http://www.ebiotrade.com/newsf/2014-4/201443122203855.htm
WebIn addition, we revealed that S-guanylation of SNAP-25 increases SNARE complex formation, but decreases the affinity of SNARE complex for complexin. Since SNAP-25 plays a critical role in regulating exocytosis, it is important to elucidate the physiological or pathophysiological meanings of S-guanylation of this protein.
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